James White top-scored with 18 points, adding four rebounds and four assists
Reggio Emilia pulled away in the final period to defeat Cholet Basket 82-65 as EuroChallenge Group J qualification goes down to the wire.
The visiting team from France was eliminated from contention, but Cholet Basket battled hard to keep the game close through three quarters.
James White stepped up for the home team in the fourth quarter, inspiring the 12-2 run to open the period as Reggio Emilia's lead stretched to 17.
The Italian team were comfortable thereafter and now face a challenging trip to Slovenia to play Krka Novo Mesto on 25 February.
Cholet Basket played well but they were let down by poor shooting as Reggio Emilia battled to restrict easy baskets.
The hosts' superior size was a problem all evening, with Ojars Silins and Angelo Gigli taking advantage inside. Gigli was enjoying his first European game for the Italian club since 2003, and he finished with eight points and nine rebounds.
White totalled 18 points, four rebounds and four assists while Silins finished with 14 points and four boards. Veteran Lithuanian playmaker Rimantas Kaukenas added 14 points and five assists in leading the hosts to victory.
Cholet Basket were led by 17 points from Torey Thomas, while Rudy Jomby added 15. The French team head to Szolnoki Olaj for the final Group J match on 25 February.