Lavezzini Basket Parma travel to Gambrinus Brno for Tuesday's last 16 FIBA EuroLeague Women clash without three key players.
Greek Olympic shooting guard Anastasia Kostaki and Italian centers Dubravka Dacic and Federica Ciampoli are all out through injuries.
|Federica Ciampoli is unavailable for the trip to Brno|
Although Croatian-born Dacic has recovered from a serious ankle injury, she has remained in Parma as she has yet to recover her top form.
The absence of the trio hindered the Gialloblu in their 87-77 league defeat at Rovereto on Saturday.
Miodrag Veskovic's outfit are hoping that recent signing Chandi Jones will inspire the team to victory.
The former Detroit Shock guard, considered one of America's young rising talents, will make her debut on Tuesday.
It's no surprise that the Czech champions are considered favourites as their squad is loaded with players who participated at the Olympics.
Brno showed they are rich in talent by winning 10 of their 12 games in Group A.
The second leg will be played back in Italy on Friday.
Brno have reached the semi-finals four times in the past six years but have never made it through to the final.