Portugal, Sweden and Ireland both posted their seconds wins of the EuroBasket Women Division B season while Montenegro edged the Netherlands in an 82-80 thriller.
Joana Lopez had 16 points and seven rebounds as the Portuguese thrashed Luxembourg, 80-32.
The game was all but over at the end of the first quarter when Portugal had a 26-5 stranglehold on proceedings.
Hermann Paar, the Luxembourg coach, said: "I have to be ashamed. This is not acceptable and is not what we can play.
"If the team plays like that again, I will resign. I don't want to live this again."
Portugal coach Carlos Portugal was very pleased.
"We played very well," he said.
"Luxembourg is not as bad as it seemed.
"We had a very good game, so we can gain some trust for the next game against FYROM."
Jil Haentges had seven points, four rebounds and three assists for Luxembourg.
Sweden lowered the boom on Estonia, 76-45.
Louice Halvarsson scored 15 points and hauled in five rebounds for the Swedes.
Sweden boss Milan Veverka said: "I was a little bit afraid of this game. Last year's first home game had the same feeling.
"With parents and family in the stands, I think the players were nervous. They wanted to show everybody how good they really are, especially after that win in Portugal. We played a good defensive game tonight.
Portugal are 2-1 in Group B while Sweden are a perfect 2-0.
Montenegro are a perfect 3-0 after their narrow win over the Netherlands (2-1).
The Montenegrins trailed by six heading into the final quarter but outscored the Dutch 22-14 to claim the two-point win.
In Group A, Ireland improved to 2-1 as well after Michelle Aspell scored 25 points in a 79-65 victory at Switzerland.
Slovenia defeated Iceland 94-69 to leave both sides at 1-2.