Fenerbahce rolled to a 78-56 victory at Tarbes GB on Wednesday night to stay unbeaten in Group B and drop the French club to 0-4.
Tarbes gave as good as they got for more than half the game but finally caved in against Turkish giants early in the third quarter.
With the score tied at 36-36, Angel McCoughtry sank two free-throws and Zane Tamane made a jumper to start a 15-4 run that put the visitors in command.
By the end of the third quarter, Fener had a 61-46 lead and they outscored Tarbes 17-10 over the last 10 minutes to clinch a 78-56 victory.
McCoughtry's 16 points led Fener (4-0), who also 14 from Penny Taylor and 12 from Nevriye Yilmaz.
Paoline Salagnac had 16 points in defeat.
Fenerbahce made all 17 of their free-throws and sank five of their 10 attempts from long range.
Birsal Vardarli, the Turkey national team point guard, hit all three of her shots from behind the arc for her nine points and also dished out five assists.
Fenerbahce Head Coach George Dikeoulakos
"We play better and better, we were not happy with the players early in the game."
Tarbes Head Coach Pascal Pisan
"Yilmaz is the best pivot in Europe. It has come to get her out in 2nd quarter time. Fenerbahce had a very strong rhythm and we have not been dangerous from outside."
Fenerbahce player Zane Tamane
"Tarbes is a good team, it is beaten, we want to win the EuroLeague Women."
Tarbes player Ana Cata-Chitiga
"Fenerbahce was stronger than we were, it was very difficult to take rebounds. I think we need to work more."