Ros Casares bounced back from last week's home defeat to Prague with a 77-50 demolition of Bourges Basket in France.
Natalia Hejkova's side raced into a 21-4 lead less than nine minutes into the game and never looked back.
Sancho Lyttle had six of her 16 points in that early spurt.
Ros put the result beyond doubt in the second quarter when they stretched their advantage to 44-20.
Eshaya Murphy had 12 points for the Spanish team at the break.
The rest of the contest was an exercise in damage limitation for Bourges, who were out-rebounded 40-25.
Ros Casares improved to 4-1 in Group A and Bourges, who played without veteran playmaker Celine Dumerc, slumped to 2-3.