Her biggest shot snapped a 73-73 tie and shortly after, Anete Jekabsone-Zogota nailed a jumper for a five-point advantage.
After Isabelle Yacoubou-Dehoui made a lay-up for Tarbes with 2:58 to go to close the gap to 78-75, Spartak knew they were in for a tight finish.
Both sides failed to score the rest of the way, however.
The final minute saw Janell McCarville miss a jump shot for Spartak, but after Tarbes' Frida Eldebrink grabbed the rebound, she had her pass intercepted by Irina Osipova.
Taurasi was off target with a jumper 33 seconds from the end but Eldebrink was whistled for travelling as Spartak held on.
Sylvia Fowles scored 17 points for Spartak (9-0) while for Tarbes, Eldebrink scored 19.
Tarbes missed out on the bid to claim a third win in their quest for a fourth-place finish.
They will go for win number three next week at Fenerbahce and if they get it, they have a chance of qualifying for the Eighth-Final Play-offs.
Spartak Moscow Region player, Ilona Korstin:
"We come from three consecutive games on the road before arriving to Tarbes. I think we were tired and it showed..."
Tarbes coach, Francois Gomez :
"We tried to forget that we play against such a great club - we didn't want to repeat the same mistake we did in Moscow. We have one game left, in Istanbul, we want to go and win it!"
Tarbes player, Isis Arrondo:
"We knew who we play against. I want to say that we knew we can compete against them but only if keep fighting during 40 minutes; it is hard to do better than that."