Looking to keep pace with Group C leaders UMMC Ekaterinburg, Ros claimed a 91-61 victory although they didn't take command until the second quarter.
Leading 27-25 with 5:39 to go in the first half, Amaya Valdemoro made two free throws to trigger a 9-0 run that was capped by a Roneeka Hodges three-pointer.
Just three seconds into the second half, Hodges drilled another three-pointer and Ros pulled away for a decisive victory.
Valdemoro scored 19 points and Delish Milton-Jones 17 for Ros.
Hodges finished with 13 points for the Spanish giants who nailed nine of 20 shots from behind the arc.