Turkey encountered resistance early on but pulled away from Italy in the second quarter on Saturday for an 80-61 win - their seventh triumph in eight games in EuroBasket Women 2009 qualifying Group B.
The triumph has sealed first place for the Turks, who had already clinched a place in next year's Final Round in Latvia.
Poland, who split their two games with Turkey, can also finish 7-1 with a win over Bosnia and Herzegovina on Saturday, but the Turks would win the tie-breaker as they had a better goal differential in the games between the two.
Saturday's setback for Italy has left them at 4-4. They can now only make it to Latvia if they are successful in next year's Additional Qualifying Round.
The Azzurre only trailed 19-18 after Chiara Pastore drilled a three-pointer late in the first quarter but Turkey reeled off the next 10 points to take command for good.
Nevriye Yilmaz had 13 points to lead a balanced Turkey scoring attack.
Maria Franchini also poured in 13 to lead the Italians.