Beretta-Famila Schio trailed for most of the second half but claimed a late 68-67 win at Frisco Sika Brno on Wednesday evening.
Liron Cohen hit a go-ahead three-ball with 55 seconds to go that proved to be the last points of the game.
Brno's last chance was a Romana Hejdova attempt from the arc with one second to go but the shot stayed out.
The Italian giants improved to 4-2 in Group D with the win while Brno dropped to 1-5.
Cheryl Ford carried Brno for much of the game, scoring 23 points, corralling 12 rebounds and coming up with three steals.
France international Isabelle Yacoubou-Dehoui continued her fine play for Schio with 21 points - including nine in the pivotal fourth quarter.
Brno seemed to be moving towards victory at the start of the fourth quarter when Romana Stehlíková's jumper gave them a 62-49 lead.
A Cohen three-pointer triggered a 9-0 run for Schio, with Yacoubou contributing a pair of baskets.
With 2:01 to go, Brno were battling and Ford scored her last two points with a jumper for a 67-63 lead.
Laura Macchi replied with a lay-up before Cohen hit the shot from the arc that put the visitors in front to stay.
Jelena Skerovic had eight points and nine assists for Brno.
Schio were 14 of 15 (93.3%) at the free-throw line while Brno made eight of 13 (61.5%).
Jan Bobrovský, Head Coach Frisco Sika Brno:
"The game took the same course as our last performance against Bourges. Today we have led with even bigger difference. We can not even win when leading by fourteen points, if Ford is scoring alone. Other players must join. In conclusion, it looks as if we are afraind of something. Our loss was not because of physical fitness, but because of thinking. Although some theoretical possibility to qualify still exists. Halvarsson played very well only in the first half and Eldebrink the entire match."
Sandro Orlando, Head Coach Beretta-Famila Schio:
"It was not the same team of Brno which lost the game in Schio. I must congratulate coach Jan Bobrovsky. Brno played very good game. I am very happy that our team didn't loose the confidence. We played ball after ball, we broke our bad performance and played in the end of the game better. We had a troubles playing against Cheryl Ford and I was surprised with Stehlikova. She played very good game, very good shooting. I am pleased we beat very strong team and keep the second place in group D."